Description

Phosgene, [14C] is a carbon-14 radiolabeled isotopologue of phosgene, a highly reactive and versatile chemical intermediate. This labeled compound is essential for advanced research and development, enabling precise metabolic and environmental fate studies. It is primarily utilized by pharmaceutical, agrochemical, and environmental research organizations for tracer studies, reaction mechanism elucidation, and analytical method development.

Application

• Tracer Studies in Pharmaceutical R&D: Used to investigate the metabolic pathways and pharmacokinetics of novel drug candidates synthesized via phosgene-mediated reactions.
• Mechanistic Research in Organic Chemistry: Employed to elucidate reaction mechanisms and identify intermediates in processes like chloroformylation and isocyanate synthesis.
• Environmental Fate and Degradation Studies: Applied to trace the environmental breakdown products and persistence of phosgene and related compounds.
• Analytical Method Development: Serves as a critical standard for developing and validating sensitive detection methods, such as LC-MS and radio-HPLC, for phosgene and its derivatives.
• Agrochemical Research: Used in the development and safety assessment of pesticides and herbicides where phosgene chemistry is involved.
• Polymer Science Investigations: Facilitates the study of polymerization kinetics and material properties in the production of polycarbonates and polyurethanes.

Basic Information

Item	Detail
Product Name	Phosgene, [14C]
CAS No.	58420-88-5
Molecular Formula	C*Cl₂O (* denotes 14C)
Molecular Weight	Contact for details
Synonyms	Carbonyl chloride-14C; [14C]Phosgene; Carbonyl dichloride-14C; CG-14C; Carbonic dichloride-14C; Chloroformyl chloride-14C
EINECS	Contact for details

Quality Control

Every batch of Phosgene, [14C] is manufactured and analyzed under stringent quality protocols to ensure high chemical and radiochemical purity, as well as specific activity consistency. Our quality systems ensure traceability and compliance with relevant guidelines for handling radioactive materials. A comprehensive Certificate of Analysis (COA) detailing identity, purity, specific activity, and solvent composition is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile and reactive nature, this material must be stored in a dedicated, well-ventilated area designated for radiochemicals, at temperatures recommended on the label or COA. Always refer to the Safety Data Sheet for complete handling and storage instructions.

Specification

Item	Specification
Appearance	Colorless solution (as specified)
Identification (IR / NMR)	Conforms to structure
Chemical Purity (GC / HPLC)	≥ 98%
Radiochemical Purity (Radio-HPLC / TLC)	≥ 97%
Specific Activity	As per customer requirement (mCi/mmol)
Concentration	As per customer requirement
Solvent	Specified (e.g., Toluene, Hexane)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.