Description

Phosphonium, (Difluoromethyl)Triphenyl-, Bromide (1:1) is a specialized organophosphorus salt widely utilized as a key reagent in advanced organic synthesis. Its primary value lies in its role as a precursor for generating the (difluoromethyl)triphenylphosphonium ylide, a versatile intermediate for introducing the difluoromethyl group into target molecules. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries, enabling the synthesis of novel fluorinated compounds with enhanced biological activity and physical properties.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs) containing difluoromethyl motifs, which can improve metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides where the difluoromethyl group is incorporated to enhance efficacy and environmental profile.
• Material Science Research: Serves as a reagent for creating fluorinated polymers, liquid crystals, and other advanced materials with unique electronic and surface properties.
• Organic Synthesis Reagent: Employed in Wittig-type olefination reactions to prepare difluoromethyl-substituted alkenes, which are valuable intermediates in complex molecule construction.
• Fluorine Chemistry: A fundamental tool for medicinal and synthetic chemists exploring structure-activity relationships (SAR) by introducing fluorine atoms into lead compounds.

Basic Information

Product Name	Phosphonium, (Difluoromethyl)Triphenyl-, Bromide (1:1)
CAS No.	58310-28-4
Molecular Formula	C19H16BrF2P
Molecular Weight	393.21 g/mol
Synonyms	(Difluoromethyl)triphenylphosphonium Bromide; Triphenyl(difluoromethyl)phosphonium Bromide; (Difluoromethyl)triphenylphosphonium Bromide (1:1); Phosphonium, (difluoromethyl)triphenyl-, bromide; Difluoromethyltriphenylphosphonium Bromide; (Difluoromethyl)-triphenylphosphonium Bromide; (α,α-Difluoromethyl)triphenylphosphonium Bromide
EINECS	Contact for details

Quality Control

Every batch of (Difluoromethyl)triphenylphosphonium Bromide is manufactured and tested under a strict quality management system to ensure high purity and consistency. Our products undergo rigorous quality testing, including HPLC, NMR, and elemental analysis, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your R&D and quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.