Description

Serotonin-D4 CAS NO 58264-95-2 is a stable isotope-labeled analog of the essential neurotransmitter serotonin, where four hydrogen atoms are replaced by deuterium. This precise labeling is critical for ensuring accuracy and reliability in quantitative analytical techniques, eliminating interference from endogenous compounds. It is an indispensable internal standard for researchers and quality control laboratories in the pharmaceutical, clinical diagnostics, and neurochemical research sectors who require the highest level of data integrity.

Application

• LC-MS/MS Internal Standard: Primary use as a quantitative reference standard in liquid chromatography-tandem mass spectrometry for accurate measurement of serotonin levels in biological matrices like plasma, serum, and cerebrospinal fluid.
• Pharmacokinetic & Metabolomic Studies: Enables precise tracking of serotonin metabolism, absorption, and distribution in drug development and clinical research.
• Diagnostic Assay Development: Used in the calibration and validation of commercial and in-house diagnostic kits for neurological and endocrine disorders.
• Neurochemical Research: Facilitates advanced research into serotonin pathways, receptor interactions, and the etiology of related psychiatric conditions.
• Quality Control & Method Validation: Serves as a critical component in GLP/GMP environments for validating analytical methods and ensuring batch-to-batch consistency in pharmaceutical manufacturing.

Basic Information

Product Name	Serotonin-D4
CAS No.	58264-95-2
Molecular Formula	C10H8D4N2O
Molecular Weight	180.23 g/mol
Synonyms	5-Hydroxytryptamine-d4; 3-(2-Aminoethyl)-1H-indol-5-ol-d4; 5-HT-d4; Serotonin (side chain-β,β,2,2-d4); Deuterated Serotonin; [2,2,β,β-2H4]-5-Hydroxytryptamine; 5-Hydroxytryptamine-1,1,2,2-d4
EINECS	Contact for details

Quality Control

Every batch of Serotonin-D4 is manufactured and analyzed under strict quality systems. We provide comprehensive Certificates of Analysis (COA) detailing isotopic purity, chemical purity, and identity confirmation via advanced spectroscopic and chromatographic methods. Our quality commitment ensures the material meets the stringent requirements for use as a certified reference material in regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, cool place. This compound is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity	≥ 98.0 atom % D
Chemical Purity	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.