Description

3-Cyanothiophene-2-Carboxylic Acid is a versatile heterocyclic building block of significant importance in advanced organic synthesis. Its bifunctional structure, featuring both a carboxylic acid and a nitrile group on a thiophene scaffold, makes it a critical precursor for constructing complex molecular architectures. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the thiophene moiety can impart specific biological activity.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the synthesis of conductive polymers, organic semiconductors, and specialty polymers.
• Ligand and Catalyst Development: The carboxylic acid group allows for coordination to metal centers, making it useful for creating novel ligands in catalysis.
• Chemical Research & Development: Employed as a versatile scaffold in academic and industrial R&D for exploring new chemical spaces and reaction pathways.
• Fine Chemical Production: Acts as a building block for synthesizing dyes, pigments, and other high-value specialty chemicals.

Basic Information

Item	Details
Product Name	3-Cyanothiophene-2-Carboxylic Acid
CAS No.	58231-00-8
Molecular Formula	C6H3NO2S
Molecular Weight	153.16 g/mol
Synonyms	2-Thiophenecarboxylic acid, 3-cyano-; 3-Cyano-2-thiophenecarboxylic acid; 3-Cyanothiophene-2-carboxylic acid; 2-Carboxy-3-cyanothiophene; 3-Cyano-thiophene-2-carboxylic acid; 3-CN-Thiophene-2-COOH; 58231-00-8 (CAS)
EINECS	Contact for details

Quality Control

Every batch of 3-Cyanothiophene-2-Carboxylic Acid is manufactured and tested under a strict quality management system. We ensure compliance with high-purity standards suitable for research and industrial synthesis. Comprehensive analytical testing, including HPLC for purity and identity confirmation, is performed. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.