Description

Ethyl 5-Amino-4-Cyano-3-(2-Ethoxy-2-Oxoethyl)Thiophene-2-Carboxylate is a high-purity, multifunctional thiophene derivative serving as a critical advanced intermediate in organic synthesis. Its molecular architecture, featuring amino, cyano, and ester functionalities, makes it a versatile building block for constructing complex heterocyclic systems. This compound is essential for research and development chemists and manufacturers in the pharmaceutical and agrochemical sectors, where it is used to develop novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Organic Electronics: Serves as a building block for π-conjugated molecules used in organic semiconductors, OLEDs, and sensors.
• Dye and Pigment Manufacturing: Employed in the synthesis of specialized heterocyclic dyes and functional pigments.
• Material Science Research: Utilized as a monomer or cross-linking agent in the development of advanced polymers and functional materials.
• Chemical Research & Development: A valuable scaffold for medicinal chemistry and method development in academic and industrial R&D laboratories.

Basic Information

Product Name	Ethyl 5-Amino-4-Cyano-3-(2-Ethoxy-2-Oxoethyl)Thiophene-2-Carboxylate
CAS No.	58168-20-0
Molecular Formula	C₁₂H₁₄N₂O₄S
Molecular Weight	282.32 g/mol
Synonyms	Ethyl 5-Amino-4-cyano-3-(2-ethoxy-2-oxoethyl)thiophene-2-carboxylate; 2-Thiophenecarboxylic acid, 5-amino-4-cyano-3-(2-ethoxy-2-oxoethyl)-, ethyl ester; 5-Amino-4-cyano-3-(carbethoxymethyl)thiophene-2-carboxylic acid ethyl ester; Ethyl 5-amino-4-cyano-3-(carbethoxymethyl)thiophene-2-carboxylate; 3-(2-Ethoxy-2-oxoethyl)-5-amino-4-cyanothiophene-2-carboxylic acid ethyl ester; Amino-CN-Thiophene Ester Derivative; ACTE Thiophene Ester
EINECS	Contact for details

Quality Control

Our Ethyl 5-Amino-4-Cyano-3-(2-Ethoxy-2-Oxoethyl)Thiophene-2-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.