Description

Isoquinoline, 3-Chloro-5-Fluoro- CAS NO 58142-53-3 is a high-purity halogenated isoquinoline derivative, a crucial building block in advanced organic synthesis. Its unique molecular structure, featuring both chloro and fluoro substituents, makes it a versatile intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, oncology, and infectious diseases.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the halogenated isoquinoline core contributes to biological activity and stability.
• Material Science Research: Serves as a precursor for developing specialty chemicals, ligands for catalysis, and organic electronic materials.
• Chemical Research & Development: An essential building block in academic and industrial R&D for exploring new heterocyclic compounds and reaction pathways.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value fine chemicals and dyes.

Basic Information

Item	Detail
Product Name	Isoquinoline, 3-Chloro-5-Fluoro-
CAS No.	58142-53-3
Molecular Formula	C9H5ClFN
Molecular Weight	181.60 g/mol
Synonyms	3-Chloro-5-fluoroisoquinoline; 5-Fluoro-3-chloroisoquinoline; 3-Chloro-5-fluoro-isoquinoline; Isoquinoline, 3-chloro-5-fluoro-; 3-Cl-5-F-Isoquinoline; 58142-53-3; 3-Chloro-5-fluoro-1-azanaphthalene
EINECS	Contact for details

Quality Control

Every batch of 3-Chloro-5-Fluoroisoquinoline is manufactured under strict quality management systems. We guarantee high chemical purity and consistency, supported by comprehensive analytical testing including HPLC, GC, and NMR. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to ensure it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.