Description

3-Chloro-n-(3-Cyano-4,5,6,7-Tetrahydro-1-Benzothien-2-Yl)Propanamide is a high-purity, heterocyclic organic compound featuring a tetrahydrobenzothiophene core, a cyano group, and a chloro-substituted propanamide side chain. This specific molecular architecture makes it a critical advanced intermediate for the synthesis of complex active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing novel therapeutic agents and crop protection solutions.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, or metabolic diseases.
• Agrochemical Synthesis: Serves as a precursor for developing new-generation herbicides, fungicides, or insecticides with specific modes of action.
• Material Science Research: Used in the development of specialty polymers, liquid crystals, or organic electronic materials due to its fused heterocyclic structure.
• Chemical Biology & Proteomics: Can be utilized as a scaffold or linker for creating chemical probes to study enzyme function or protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring high-purity, complex intermediates.

Basic Information

Product Name	3-Chloro-n-(3-Cyano-4,5,6,7-Tetrahydro-1-Benzothien-2-Yl)Propanamide
CAS No.	58125-41-0
Molecular Formula	C₁₂H₁₃ClN₂OS
Molecular Weight	268.76 g/mol
Synonyms	2-[(3-Chloropropanoyl)amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carbonitrile; 3-Chloro-N-(3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)propanamide; 3-Chloro-N-(3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)propanamide; Propanamide, 3-chloro-N-(3-cyano-4,5,6,7-tetrahydro-1-benzothien-2-yl)-; 58125-41-0; Tetrahydrobenzothiophene propanamide derivative
EINECS	Contact for details

Quality Control

Our production of 3-Chloro-n-(3-Cyano-4,5,6,7-Tetrahydro-1-Benzothien-2-Yl)Propanamide adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the exacting standards required for pharmaceutical and agrochemical applications. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.