Description

2-Amino-4-Cyclopropylthiophene-3-Carbonitrile is a high-purity, advanced pharmaceutical intermediate characterized by its unique thiophene core substituted with amino, cyclopropyl, and nitrile functional groups. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of complex molecules with targeted biological activity. It is primarily needed by R&D and production teams in the pharmaceutical and agrochemical industries for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, leveraging its heterocyclic structure for bioactivity.
• Material Science Research: Serves as a monomer or functional unit in the development of specialty polymers and organic electronic materials.
• Chemical Biology Probes: Employed in academic and industrial research to create molecular probes for studying enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and production under cGMP conditions.

Basic Information

Product Name	2-Amino-4-Cyclopropylthiophene-3-Carbonitrile
CAS No.	58124-28-0
Molecular Formula	C8H8N2S
Molecular Weight	164.23 g/mol
Synonyms	2-Amino-4-cyclopropyl-3-thiophenecarbonitrile; 4-Cyclopropyl-2-aminothiophene-3-carbonitrile; 3-Cyano-4-cyclopropyl-2-aminothiophene; 2-Amino-4-cyclopropylthiophene-3-carbonitrile; 3-Thiophenecarbonitrile, 2-amino-4-cyclopropyl-; 58124-28-0; 2-Amino-4-(cyclopropyl)thiophene-3-carbonitrile
EINECS	Contact for details

Quality Control

Our 2-Amino-4-Cyclopropylthiophene-3-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Production can be aligned with cGMP guidelines for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.