Description

3-Acetyl-5-Chlorothiophene is a high-purity, versatile heterocyclic building block essential for advanced organic synthesis. This compound is valued for its reactive acetyl and chloro substituents on the thiophene ring, enabling precise molecular construction. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and fungicides, leveraging the thiophene scaffold for enhanced bioactivity.
• Material Science Research: Serves as a monomer or functional unit in the creation of conductive polymers, organic semiconductors, and specialty polymers.
• Organic Light-Emitting Diodes (OLEDs): Employed in the research and development of electron-transport materials and emissive layers for display technologies.
• Ligand and Catalyst Development: Acts as a starting material for synthesizing specialized ligands used in transition metal catalysis and coordination chemistry.
• Custom Synthesis and Contract Manufacturing: A critical raw material for fine chemical producers engaged in custom synthesis projects for clients worldwide.

Basic Information

Product Name	3-Acetyl-5-Chlorothiophene
CAS No.	58119-67-8
Molecular Formula	C6H5ClOS
Molecular Weight	160.62 g/mol
Synonyms	1-(5-Chloro-3-thienyl)ethanone; 5-Chloro-3-acetylthiophene; 3-Acetyl-5-chlorothiophene; 5-Chloro-3-thienyl methyl ketone; 1-(5-Chlorothiophen-3-yl)ethan-1-one; 3-Acetyl-5-chloro-thiophene; 5-Chloro-3-thiophenecarbaldehyde, acetyl derivative
EINECS	Contact for details

Quality Control

Our 3-Acetyl-5-Chlorothiophene is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide full traceability and a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.