Description

(1R,5S)-Bicyclo[3.1.0]Hexan-2-One CAS NO 58001-78-8 is a high-purity, chiral bicyclic ketone of significant interest in advanced organic synthesis. Its unique strained ring structure and defined stereochemistry make it a valuable and versatile building block for creating complex molecular architectures. This compound is particularly essential for researchers and process chemists in the pharmaceutical and agrochemical industries, where it serves as a key intermediate in the development of active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of prostaglandins, terpenoids, and other bioactive molecules with complex ring systems.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging its rigid bicyclic framework.
• Flavor & Fragrance Chemistry: Serves as a precursor for synthesizing specific musky or woody aroma compounds.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of specialized polymers with unique thermal or mechanical properties.
• Asymmetric Catalysis: Employed as a ligand precursor or a test substrate in the development of new chiral catalysts.
• Academic & R&D: A valuable tool for methodological studies in organic chemistry, including ring-opening reactions and stereoselective transformations.

Basic Information

Product Name	(1R,5S)-Bicyclo[3.1.0]Hexan-2-One
CAS No.	58001-78-8
Molecular Formula	C7H10O
Molecular Weight	110.15 g/mol
Synonyms	(1R,5S)-Bicyclo[3.1.0]hexan-2-one; (-)-(1R,5S)-Bicyclo[3.1.0]hexan-2-one; (1R,5S)-Bicyclo[3.1.0]hexan-2-one; Bicyclo[3.1.0]hexan-2-one, (1R,5S)-; (1R,5S)-6,6-Dimethylbicyclo[3.1.0]hexan-2-one (common misnomer); (1R,5S)-3-Oxabicyclo[3.1.0]hexane (related structure); endo-Bicyclo[3.1.0]hexan-2-one
EINECS	Contact for details

Quality Control

Our (1R,5S)-Bicyclo[3.1.0]Hexan-2-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by GC or HPLC, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Chiral Purity (Chiral GC/HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.