Description

Nicotinic Acid-13C1 is a stable isotope-labeled analog of nicotinic acid (Vitamin B3), where one carbon atom is replaced by the carbon-13 isotope. This product is essential for advanced analytical research, providing an internal standard for precise quantification and metabolic pathway tracing using techniques like mass spectrometry. It is primarily required by pharmaceutical R&D laboratories, clinical research organizations, and academic institutions engaged in pharmacokinetic studies, biomarker discovery, and nutritional science.

Application

• Internal Standard for Quantitative Analysis: Used in LC-MS and GC-MS methods for the accurate measurement of nicotinic acid and its metabolites in complex biological matrices.
• Metabolic Pathway Tracing: Enables the study of niacin metabolism, absorption, and distribution in nutritional and pharmacological research.
• Drug Development and Pharmacokinetics (PK/PD): Critical for conducting mass balance studies and determining the bioavailability of new drug formulations containing niacin.
• Clinical Diagnostics: Serves as a reference standard in assays designed to diagnose niacin deficiency or monitor niacin levels in patient samples.
• Nutritional Research: Facilitates the investigation of Vitamin B3's role in cellular energy production and lipid metabolism.
• Isotope Dilution Mass Spectrometry (IDMS): Provides the highest accuracy and precision for certification of reference materials and method validation.

Basic Information

Product Name	Nicotinic Acid-13C1
CAS No.	57987-14-1
Molecular Formula	C513CH5NO2
Molecular Weight	124.10 g/mol (for 13C1 labeled form)
Synonyms	3-Pyridinecarboxylic Acid-13C1; Vitamin B3-13C1; Niacin-13C1; Pyridine-3-carboxylic Acid-13C1; 13C Labeled Nicotinic Acid; [13C1]-Nicotinic Acid; 3-Carboxypyridine-13C1
EINECS	Contact for details

Quality Control

Every batch of Nicotinic Acid-13C1 is manufactured and tested under a strict quality management system. We guarantee high chemical and isotopic purity, with comprehensive testing including NMR, HPLC, and MS to confirm structure, purity, and isotopic enrichment. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting batch-specific results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (MS)	≥ 99 atom % 13C
Chemical Purity	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.