Description

1-Bromo-2-Cyclopropylethyne is a versatile and highly reactive halogenated alkyne building block, essential for advanced organic synthesis. Its unique structure, featuring a cyclopropyl group adjacent to a bromoethynyl moiety, makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and material science industries for applications such as cross-coupling reactions and the synthesis of novel bioactive compounds.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates, particularly in cyclopropane-containing molecules.
• Agrochemical Synthesis: Used in the research and development of new pesticides, herbicides, and fungicides that require the cyclopropane ring for biological activity.
• Material Science Precursor: Acts as a monomer or cross-linking agent in the development of advanced polymers and functional materials with tailored properties.
• Cross-Coupling Reactions: An excellent substrate for Sonogashira, Heck, and other palladium-catalyzed coupling reactions to form complex conjugated systems.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands and organometallic catalysts for asymmetric synthesis.
• Chemical Research: A valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and reaction pathways.

Basic Information

Product Name	1-Bromo-2-Cyclopropylethyne
CAS No.	57951-72-1
Molecular Formula	C5H5Br
Molecular Weight	145.00 g/mol
Synonyms	2-Cyclopropyl-1-bromoethyne; Bromo(cyclopropyl)acetylene; Cyclopropylbromoacetylene; 1-Bromo-2-cyclopropylacetylene; Bromocyclopropylacetylene; (Bromoethynyl)cyclopropane; Ethyne, bromo(cyclopropyl)-; 57951-72-1
EINECS	Contact for details

Quality Control

Our 1-Bromo-2-Cyclopropylethyne is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and scale-up applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as purity, identity, and impurity profiles. Our quality management system is designed to meet the rigorous standards demanded by the fine chemical and pharmaceutical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive and should be handled under an inert atmosphere when appropriate to maintain stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.