Description

Bromoacetic-1-13C Acid is a stable isotope-labeled derivative of bromoacetic acid, where the carbon-1 position is enriched with the 13C isotope. This precise labeling is critical for applications requiring high-sensitivity detection and accurate metabolic pathway tracing in research. It is an essential building block for pharmaceutical, agrochemical, and biochemical research scientists who require isotopically labeled compounds for advanced analytical studies, including NMR spectroscopy and mass spectrometry.

Application

• Pharmaceutical Research & Development: Used as a 13C-labeled intermediate in the synthesis of novel Active Pharmaceutical Ingredients (APIs) for drug metabolism and pharmacokinetics (DMPK) studies.
• Metabolic Pathway Analysis: Serves as a tracer compound in biochemical research to elucidate metabolic fluxes and mechanisms using techniques like GC-MS and LC-MS.
• Agrochemical Synthesis: Employed in the development of isotopically labeled herbicides, pesticides, and plant growth regulators for environmental fate and residue analysis.
• NMR Spectroscopy Standard: Acts as a chemical shift reference or a building block for synthesizing more complex 13C-labeled NMR probes and standards.
• Proteomics & Biomarker Discovery: Utilized in chemical proteomics for activity-based protein profiling (ABPP) and the synthesis of isotopically coded affinity tags.
• Material Science Research: Functions as a monomer or modifying agent in the synthesis of specialty polymers and advanced materials with traceable 13C labels.

Basic Information

Item	Detail
Product Name	Bromoacetic-1-13C Acid
CAS No.	57858-24-9
Molecular Formula	C13CH2BrCOOH
Molecular Weight	138.94 g/mol (for 13C labeled)
Synonyms	2-Bromoacetic-1-13C Acid; (1-13C)Bromoacetic Acid; Bromoacetic Acid-1-13C; Monobromoacetic-1-13C Acid; Carboxy-13C Bromomethane; α-Bromoacetic-1-13C Acid; MBA-1-13C; 13C Labeled Bromoacetic Acid
EINECS	Contact for details

Quality Control

Every batch of Bromoacetic-1-13C Acid is produced and tested under strict quality management protocols to ensure exceptional isotopic and chemical purity, critical for sensitive research applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing isotopic enrichment, chemical purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and a strong acid/organic solvent; ensure containers are kept tightly sealed to exclude moisture and are stored separately from bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Isotopic Enrichment (13C)	≥ 99 atom %
Assay (HPLC)	≥ 98.0% (chemical purity)
Water Content (KF)	≤ 0.5%
Melting Point	49 - 52 °C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.