Description

7-tert-Butyl-1H-Indole-2,3-Dione is a high-purity, synthetically derived isatin derivative, a versatile chemical intermediate prized for its unique sterically hindered tert-butyl substituent. This structural feature makes it a critical building block for advanced organic synthesis, enabling the development of novel compounds with tailored properties. It is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to create new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, due to the isatin core's biological relevance.
• Agrochemical Research: Used in developing new herbicides, fungicides, and plant growth regulators, where the tert-butyl group can enhance lipophilicity and environmental stability.
• Organic Synthesis Building Block: A versatile starting material for constructing complex heterocyclic compounds, including spirooxindoles and other fused ring systems important in medicinal chemistry.
• Material Science: Investigated for the development of organic semiconductors, dyes, and pigments, where its electron-accepting properties and molecular structure are advantageous.
• Biochemical Research: Employed as a scaffold or inhibitor in enzymatic studies and proteomics research to explore protein-ligand interactions.
• Catalyst & Ligand Development: Utilized to synthesize novel ligands for transition metal catalysts used in asymmetric synthesis and cross-coupling reactions.

Basic Information

Product Name	7-tert-Butyl-1H-Indole-2,3-Dione
CAS No.	57817-00-2
Molecular Formula	C₁₂H₁₃NO₂
Molecular Weight	203.24 g/mol
Synonyms	7-tert-Butylisatin; 7-(1,1-Dimethylethyl)-1H-indole-2,3-dione; 7-tert-Butyl-2,3-dihydro-1H-indole-2,3-dione; 7-tert-Butyl-2,3-indolinedione; 7-tert-Butyl-1H-indole-2,3-dione; 7-(tert-Butyl)isatin; 7-tert-Butyl-2,3-dioxoindoline
EINECS	Contact for details

Quality Control

Our 7-tert-Butyl-1H-Indole-2,3-Dione is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and industrial applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. The product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.