Description

Closantel is a potent salicylanilide derivative with significant anthelmintic activity. Its primary value lies in its high efficacy against a broad spectrum of parasitic nematodes and trematodes, particularly liver flukes. This makes it a critical active pharmaceutical ingredient (API) for the veterinary pharmaceutical industry. Manufacturers of veterinary injectables, drenches, and feed additives rely on high-purity Closantel CAS NO 57808-65-8 to ensure product safety and therapeutic effectiveness.

Application

• Primary Active Pharmaceutical Ingredient (API) in veterinary anthelmintic formulations.
• Manufacturing of injectable solutions for the treatment of liver fluke (Fasciola hepatica) infections in cattle and sheep.
• Key component in oral drenches and pour-on preparations for parasite control in livestock.
• Used in combination therapies to broaden the spectrum of activity against gastrointestinal nematodes.
• Research and development of new antiparasitic drugs and delivery systems.
• Reference standard for quality control and analytical testing in pharmaceutical laboratories.

Basic Information

Product Name	Closantel
CAS No.	57808-65-8
Molecular Formula	C22H14Cl2I2N2O2
Molecular Weight	663.07 g/mol
Synonyms	N-[5-Chloro-4-[(4-chlorophenyl)cyanomethyl]-2-methylphenyl]-2-hydroxy-3,5-diiodobenzamide; Closantel Sodium; 4'-Chloro-3,5-diiodosalicylanilide-4-chloro-α-cyan-o-toluidide; Seponver; Flukiver; Curatrem; Zanil
EINECS	Contact for details

Quality Control

Our Closantel is manufactured under strict quality management systems to ensure it meets the rigorous standards required for pharmaceutical use. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via HPLC. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Yellow to orange-yellow crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water (KF)	≤ 1.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.