Description

1-Cyclopropyl-2-Iodobenzene is a high-purity, advanced organic intermediate featuring a cyclopropyl group ortho to an iodine substituent on a benzene ring. This specific substitution pattern makes it a valuable and versatile building block for constructing complex molecular architectures in pharmaceutical and agrochemical research. It is primarily utilized by R&D chemists and process development scientists in the fine chemical and life sciences industries. The compound's reactivity is leveraged in cross-coupling reactions and as a precursor for further functionalization.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a cyclopropyl-aryl scaffold for biological activity.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides where the cyclopropyl group can enhance stability and efficacy.
• Material Science Precursor: Serves as a monomer or building block for creating specialized organic electronic materials and liquid crystals.
• Cross-Coupling Reactions: The iodine atom acts as an excellent handle for metal-catalyzed reactions like Suzuki, Negishi, and Stille couplings to form new carbon-carbon bonds.
• Ligand Synthesis: Utilized in the preparation of sophisticated ligands for catalysis and coordination chemistry.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological systems and target engagement.

Basic Information

Product Name	1-Cyclopropyl-2-Iodobenzene
CAS No.	57807-29-1
Molecular Formula	C9H9I
Molecular Weight	244.07 g/mol
Synonyms	(2-Iodophenyl)cyclopropane; 2-Cyclopropyl-1-iodobenzene; o-Iodophenylcyclopropane; 1-Iodo-2-cyclopropylbenzene; Benzene, 1-cyclopropyl-2-iodo-; Cyclopropyl-o-iodobenzene; 2-Iodocyclopropylbenzene; 57807-29-1
EINECS	Contact for details

Quality Control

Our 1-Cyclopropyl-2-Iodobenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided for each lot to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.