Description

1-Bromo-2-Cyclopropylbenzene is a versatile halogenated aromatic building block of significant importance in advanced organic synthesis. Its unique structure, featuring a bromine atom adjacent to a cyclopropyl substituent on a benzene ring, makes it a valuable precursor for constructing complex molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in cross-coupling reactions and as a key intermediate in active ingredient development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring a substituted benzyl or aryl-cyclopropyl moiety.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides where the cyclopropylbenzene scaffold is integral to biological activity.
• Material Science Precursor: Serves as a monomer or functionalization agent in the development of specialty polymers and advanced organic materials.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl and extended conjugated systems.
• Ligand and Catalyst Development: Employed in the synthesis of novel phosphine or N-heterocyclic carbene (NHC) ligands for asymmetric catalysis.
• Chemical Research: A valuable reagent in academic and industrial R&D for methodology development and exploring new reaction pathways.

Basic Information

Product Name	1-Bromo-2-Cyclopropylbenzene
CAS No.	57807-28-0
Molecular Formula	C9H9Br
Molecular Weight	197.07 g/mol
Synonyms	2-Bromo-1-cyclopropylbenzene; (2-Bromophenyl)cyclopropane; o-Bromocyclopropylbenzene; 1-Cyclopropyl-2-bromobenzene; 2-Bromocyclopropylbenzene; Bromocyclopropylbenzene; Cyclopropylphenyl bromide
EINECS	Contact for details

Quality Control

Our 1-Bromo-2-Cyclopropylbenzene is manufactured under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatography (GC/HPLC) and spectroscopic methods (NMR, IR), to verify identity and purity against established specifications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.