Description

5-Chloro-4-Nitrothiophene-2-Carboxylic Acid Methyl Ester is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound is valued for its reactive nitro and chloro substituents on the thiophene ring, which enable precise chemical modifications. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting various therapeutic areas.
• Agrochemical Synthesis: Serves as a crucial precursor in the manufacture of advanced pesticides, herbicides, and fungicides.
• Material Science Research: Used in the synthesis of functionalized thiophene-based polymers and organic electronic materials.
• Dye and Pigment Intermediate: Employed in the production of specialized colorants and pigments due to its nitro-substituted aromatic structure.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom chemical synthesis services and scale-up production for specific client projects.
• Academic & Industrial R&D: Utilized in research laboratories for exploring new chemical reactions and synthesizing complex heterocyclic compounds.

Basic Information

Product Name	5-Chloro-4-Nitrothiophene-2-Carboxylic Acid Methyl Ester
CAS No.	57800-76-7
Molecular Formula	C7H4ClNO4S
Molecular Weight	233.63 g/mol
Synonyms	Methyl 5-chloro-4-nitrothiophene-2-carboxylate; 5-Chloro-4-nitro-2-thiophenecarboxylic acid methyl ester; 2-Thiophenecarboxylic acid, 5-chloro-4-nitro-, methyl ester; Methyl 5-chloro-4-nitro-2-thiophenecarboxylate; 57800-76-7; 5-Chloro-4-nitrothiophene-2-methyl carboxylate
EINECS	Contact for details

Quality Control

Our 5-Chloro-4-Nitrothiophene-2-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting standards for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to direct light should be avoided.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.