Description

2-Trimethylsilanylaniline is a versatile organosilicon compound featuring a primary aniline group protected by a trimethylsilyl moiety. This functional group combination makes it a valuable silylating agent and a protected aniline building block in advanced organic synthesis. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of complex molecules and intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly where a protected aniline group is required for selective reactions.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides that incorporate aniline-derived structures.
• Silylating Agent: Protects hydroxyl and amine groups in complex multi-step syntheses, improving solubility and stability of intermediates.
• Material Science Precursor: Serves as a monomer or modifying agent in the synthesis of specialized silicones, polymers, and advanced materials.
• Ligand Synthesis: Used to create novel ligands for catalysis and metal-organic frameworks (MOFs).
• Research & Development: A valuable reagent in academic and industrial labs for methodological development and exploratory chemistry.

Basic Information

Product Name	2-Trimethylsilanylaniline
CAS No.	57792-17-3
Molecular Formula	C9H15NSi
Molecular Weight	165.31 g/mol
Synonyms	2-(Trimethylsilyl)aniline; N-(Trimethylsilyl)aniline; o-(Trimethylsilyl)aniline; 2-Aminophenyltrimethylsilane; Aniline, 2-(trimethylsilyl)-; 2-TMS-aniline; 2-Trimethylsilylaniline; 2-(Trimethylsilyl)benzenamine
EINECS	Contact for details

Quality Control

Our 2-Trimethylsilanylaniline is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR to verify identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for every shipment upon request, ensuring it meets the stringent requirements for research and industrial synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.