Description

3-Isocyanato-1H-Indole is a versatile and highly reactive heterocyclic building block used in advanced organic synthesis. Its core value lies in the isocyanate functional group, which readily undergoes addition reactions with nucleophiles like amines and alcohols, enabling the construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require a precise, high-purity intermediate for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in the development of kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides with specific modes of action.
• Polymer & Material Science: Serves as a monomer or cross-linking agent for producing polyurethanes, polyureas, and other specialty polymers with tailored properties.
• Chemical Research & Development: A critical reagent in medicinal chemistry and process chemistry for constructing indole-based scaffolds and exploring new reaction pathways.
• Dye & Pigment Manufacturing: Intermediate in the synthesis of complex organic colorants and functional dyes.

Basic Information

Product Name	3-Isocyanato-1H-Indole
CAS No.	57778-78-6
Molecular Formula	C9H6N2O
Molecular Weight	158.16 g/mol
Synonyms	1H-Indol-3-yl isocyanate; 3-Isocyanatoindole; Indol-3-yl isocyanate; 3-Isocyanato-1H-indole; Isocyanic acid, 1H-indol-3-yl ester; 3-Indolyl isocyanate
EINECS	Contact for details

Quality Control

Our 3-Isocyanato-1H-Indole is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, identity confirmation (IR, NMR), and impurity profiling. A Certificate of Analysis (COA) is supplied with each shipment, detailing all relevant specifications. Our quality management system is designed to meet the stringent requirements of research and industrial-scale applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its moisture-sensitive (hygroscopic) and reactive nature. Keep away from heat, open flames, and sources of ignition. Separate from amines, alcohols, water, and other incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.