Description

1H-Indole-3-D CAS NO 57754-36-6 is a deuterated derivative of indole, a fundamental heterocyclic aromatic structure widely utilized in research and development. This labeled compound is essential for advanced analytical and synthetic applications where isotopic tracing is required. It serves as a critical building block and reference standard for pharmaceutical, agrochemical, and material science industries engaged in metabolic studies, reaction mechanism elucidation, and the development of novel compounds.

Application

• Pharmaceutical Research & Development: Used as a deuterium-labeled internal standard in Liquid Chromatography-Mass Spectrometry (LC-MS) for the precise quantification of indole-based drugs and metabolites.
• Metabolic Pathway Tracing: Employed in pharmacokinetic and drug metabolism studies to track the fate of indole scaffolds within biological systems using isotopic labeling techniques.
• Organic Synthesis Intermediate: Acts as a specialized building block for synthesizing deuterated analogs of complex molecules, including alkaloids, tryptamines, and other indole derivatives for research purposes.
• Agrochemical Development: Utilized in the research of novel plant growth regulators or pesticides where the indole structure is a key active component, allowing for mechanistic studies.
• Material Science Research: Serves as a precursor or dopant in the development of advanced organic electronic materials, such as OLEDs, where deuterium substitution can influence stability and performance.
• Analytical Reference Standard: Provides a high-purity, isotopically labeled reference material for method development and validation in analytical laboratories to ensure accuracy and compliance.

Basic Information

Product Name	1H-Indole-3-D
CAS No.	57754-36-6
Molecular Formula	C8H6DN
Molecular Weight	118.15 g/mol (for monoisotopic mass)
Synonyms	Indole-3-d; 3-Deuteroindole; 1H-Indole-3-d1; Deuterated Indole (3-position); 3-Deutero-1H-indole; [3-2H]Indole; Indole-d (3-); 2,3-Benzopyrrole-3-d
EINECS	Contact for details

Quality Control

We supply 1H-Indole-3-D in high-purity grades suitable for research and analytical applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Key parameters such as isotopic purity (D-enrichment), chemical purity (by HPLC), and identity (by NMR/IR) are strictly controlled. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and potential contamination. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.