Description

Acetic Acid-17O2 CAS NO 57745-60-5 is a stable isotope-labeled analog of acetic acid, where two oxygen atoms are replaced by the non-radioactive isotope Oxygen-17. This compound is a critical tool for advanced research, enabling precise metabolic pathway tracing, reaction mechanism elucidation, and analytical method development. It is essential for scientists and industries requiring high-fidelity isotopic labeling in NMR spectroscopy, mass spectrometry, and metabolic flux analysis.

Application

• NMR Spectroscopy: Used as an internal standard and for studying molecular structure and dynamics due to the distinct NMR signal of 17O.
• Metabolic Research & Flux Analysis: Tracks the incorporation of labeled atoms in biochemical pathways to study metabolism in cells, tissues, or organisms.
• Mass Spectrometry: Serves as a labeled internal standard for the accurate quantification of acetic acid and related metabolites in complex matrices.
• Reaction Mechanism Studies: Elucidates pathways in organic synthesis and catalytic processes by tracing the fate of the labeled oxygen atoms.
• Geochemical & Environmental Tracing: Investigates biogeochemical cycles and environmental processes involving acetate.
• Pharmaceutical Development: Utilized in drug metabolism and pharmacokinetics (DMPK) studies to understand the biotransformation of drug candidates.

Basic Information

Product Name	Acetic Acid-17O2
CAS No.	57745-60-5
Molecular Formula	C2H417O2
Molecular Weight	62.04 g/mol (approx., varies with isotopic enrichment)
Synonyms	Acetic-17O Acid; [17O2]-Acetic Acid; Acetic Acid (Oxygen-17 Labeled); Isotopic Acetic Acid-17O2; Ethanoic Acid-17O2; Glacial Acetic Acid-17O2; 17O-Labeled Acetic Acid; CH3C17O17OH
EINECS	Contact for details

Quality Control

Every batch of Acetic Acid-17O2 is produced and analyzed under stringent conditions to ensure exceptional isotopic and chemical purity. Our quality assurance protocol includes verification of isotopic enrichment (Atom % 17O) by NMR or MS, chemical purity by titration or chromatography, and confirmation of identity. A comprehensive Certificate of Analysis (COA) detailing all specifications, including isotopic purity, chemical assay, and solvent content, is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials such as strong oxidizers and bases. Due to its nature as a strong acid/organic solvent and high volatility, ensure containers are sealed when not in use and handle in a fume hood. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Colorless Liquid
Identification (IR/NMR)	Conforms to Standard
Isotopic Enrichment (Atom % 17O)	≥ 90% (Custom enrichments available)
Chemical Purity (Assay)	≥ 99.0% (by GC or Titration)
Isotopic Purity	Contact for details
Water Content	≤ 0.5% (by KF)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.