Description

1-(1H-Indol-3-Yl)-2-Iodo-Ethanone is a versatile iodinated ketone derivative of indole, serving as a key synthetic intermediate in advanced organic chemistry. This compound is valued for its reactivity, particularly in cross-coupling reactions and as a building block for complex heterocyclic systems. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of potential drug candidates, including kinase inhibitors and other biologically active indole derivatives.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators that utilize the indole scaffold.
• Material Science: Serves as a precursor for organic electronic materials, such as organic semiconductors and light-emitting diodes (OLEDs).
• Chemical Synthesis: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to form new carbon-carbon bonds.
• Academic & R&D: A valuable reagent for methodological studies and exploring new synthetic pathways in university and corporate research laboratories.
• Fluorescent Probe Development: Used in the creation of indole-based fluorescent markers and sensors for biochemical applications.

Basic Information

Product Name	1-(1H-Indol-3-Yl)-2-Iodo-Ethanone
CAS No.	57642-05-4
Molecular Formula	C10H8INO
Molecular Weight	285.08 g/mol
Synonyms	3-(Iodoacetyl)indole; 2-Iodo-1-(1H-indol-3-yl)ethanone; 1H-Indole-3-acetyl iodide; 3-Acetylindole, 2-iodo-; 3-(2-Iodoacetyl)indole; Iodoacetylindole; α-Iodo-3-indolyl methyl ketone
EINECS	Contact for details

Quality Control

Our 1-(1H-Indol-3-Yl)-2-Iodo-Ethanone is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with key parameters including assay (HPLC), related substances, and residual solvents. Our quality system supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed under an inert atmosphere to minimize degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.