Description

1H-Indazole, 7-Bromo-3-(Trifluoromethyl)- is a high-value, multi-functional heterocyclic building block, distinguished by its bromo and trifluoromethyl substituents which impart unique reactivity and physicochemical properties. This compound is critical for advanced research and development, enabling the synthesis of complex molecules with tailored biological and material characteristics. It is primarily sought after by pharmaceutical, agrochemical, and advanced material scientists for applications in drug discovery, crop protection, and specialty polymer development.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the synthesis of advanced crop protection agents, leveraging the bioactivity-enhancing properties of the trifluoromethyl group.
• Material Science: Serves as a precursor for functionalized polymers, liquid crystals, and organic electronic materials due to its rigid indazole core and halogenated motifs.
• Chemical Biology Probe Development: Employed in creating molecular probes and labeled compounds for studying biological pathways and mechanisms.
• Organic Synthesis Building Block: The bromine atom offers a versatile handle for further functionalization via cross-coupling reactions (e.g., Suzuki, Sonogashira), enabling rapid diversification of chemical libraries.

Basic Information

Product Name	1H-Indazole, 7-Bromo-3-(Trifluoromethyl)-
CAS No.	57631-12-6
Molecular Formula	C8H4BrF3N2
Molecular Weight	265.03 g/mol
Synonyms	7-Bromo-3-(trifluoromethyl)-1H-indazole; 7-Bromo-3-(trifluoromethyl)indazole; 3-Trifluoromethyl-7-bromoindazole; 7-Bromo-3-trifluoromethyl-1H-indazole; 57631-12-6; 7-Bromo-3-trifluoromethylindazole; 1H-Indazole, 7-bromo-3-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our production of 1H-Indazole, 7-Bromo-3-(Trifluoromethyl)- adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical characterization, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our commitment to reliable supply and batch-to-batch reproducibility supports your critical R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.