Description

2,2,2-Tribromoethyl Phosphoromorpholinochloridate is a specialized organophosphorus compound featuring a tribromoethyl group and a morpholinochloridate moiety. This unique structure makes it a valuable highly reactive intermediate and phosphorylating agent in advanced synthetic chemistry. It is primarily sought by pharmaceutical research and agrochemical development teams for constructing complex molecules, particularly in the synthesis of nucleotide analogs and bioactive phosphoramidates.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel antiviral and anticancer nucleotide prodrugs.
• Agrochemical Synthesis: Used in the research and development of new generation insecticides and herbicides with phosphoramidate backbones.
• Chemical Biology Probe Development: Employed to create active site-directed inhibitors and affinity labels for studying enzyme mechanisms.
• Polymer Chemistry: Serves as a monomer or cross-linking agent in the development of specialty flame-retardant polymers.
• Peptide Modification: Used for the selective phosphorylation or labeling of serine, threonine, or tyrosine residues in peptides.
• Material Science Research: Investigated for creating novel surface coatings or functional materials with specific chemical reactivity.

Basic Information

Item	Details
Product Name	2,2,2-Tribromoethyl Phosphoromorpholinochloridate
CAS No.	57575-15-2
Molecular Formula	C6H10Br3ClNO3P
Molecular Weight	449.29 g/mol
Synonyms	Phosphorochloridic acid, (2,2,2-tribromoethyl)-, morpholide; Tribromoethyl Morpholino Phosphorochloridate; 2,2,2-Tribromoethyl Morpholinophosphorochloridate; NSC 334906; (2,2,2-Tribromoethoxy)(morpholino)phosphinic chloride; Morpholine, 4-[[(2,2,2-tribromoethoxy)chlorophosphinyl]oxy]-
EINECS	Contact for details

Quality Control

Every batch of 2,2,2-Tribromoethyl Phosphoromorpholinochloridate is produced and tested under strict quality management protocols. We ensure high purity and batch-to-batch consistency through advanced analytical techniques including NMR, HPLC, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your R&D and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening. Recommended storage temperature is 2-8°C for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.