Description

L-Praziquantel is the levo-isomer of the anthelmintic compound praziquantel, a critical active pharmaceutical ingredient (API) in the global fight against parasitic worm infections. Its high purity and specific stereochemistry are essential for ensuring optimal therapeutic efficacy and safety in pharmaceutical formulations. This compound is primarily required by manufacturers in the pharmaceutical and veterinary medicine industries for the production of antiparasitic treatments.

Application

• Pharmaceutical API: Core active ingredient in human anthelmintic medications, particularly for the treatment of schistosomiasis (bilharzia) and other trematode infections.
• Veterinary Pharmaceuticals: Key component in deworming formulations for livestock, companion animals, and aquaculture, targeting tapeworms and flukes.
• Research & Development: Used as a high-purity reference standard in pharmacological studies, metabolic research, and new drug development.
• Formulation Development: Serves as the primary API in the development of various dosage forms, including tablets, suspensions, and injectables.
• Generic Drug Manufacturing: Essential for producers of generic antiparasitic drugs, ensuring bioequivalence and regulatory compliance.
• Public Health Programs: Supplied for use in mass drug administration (MDA) campaigns aimed at controlling neglected tropical diseases.

Basic Information

Product Name	L-Praziquantel
CAS No.	57452-98-9
Molecular Formula	C19H24N2O2
Molecular Weight	312.41 g/mol
Synonyms	(11bS)-2-(Cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isoquinolin-4-one; (-)-Praziquantel; Levopraziquantel; (S)-Praziquantel; Praziquantel Impurity F (EP); L-PZQ; Biltricide (stereoisomer); Droncit (stereoisomer)
EINECS	Contact for details

Quality Control

Our L-Praziquantel is manufactured under strict quality management systems to meet the exacting standards of the pharmaceutical industry. Each batch is subjected to comprehensive analytical testing, including chiral purity assay, identification, and impurity profiling via HPLC and other pharmacopeial methods. We provide full traceability and Certificates of Analysis (COA) that confirm compliance with in-house specifications and relevant guidelines. The product is suitable for use under cGMP conditions for API manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to almost white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Chiral Purity (Enantiomeric Excess)	≥ 99.0%
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 1.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.