Description

Lucanthone Hydrochloride is a synthetic organic compound belonging to the thioxanthenone class, primarily recognized for its significant historical role as an antischistosomal agent. Its value lies in its specific biochemical activity, making it a crucial reference standard and research chemical for pharmacological studies. This product is essential for researchers and developers in the pharmaceutical, biotechnology, and academic sectors investigating antiparasitic mechanisms, drug metabolism, and molecular biology.

Application

• Pharmaceutical Reference Standard: Used as a high-purity certified standard for quality control and analytical method development in drug testing laboratories.
• Biomedical Research: Serves as a key biochemical tool in in vitro and in vivo studies targeting parasitic diseases, particularly schistosomiasis.
• Mechanism of Action Studies: Employed to investigate the inhibition of topoisomerase II and other enzymatic pathways relevant to antiparasitic and potential anticancer activity.
• Metabolite Synthesis & Analysis: Acts as a precursor or standard for the synthesis and identification of metabolic derivatives in pharmacokinetic research.
• Academic & Institutional Research: Utilized in university and government labs for fundamental research in medicinal chemistry and parasitology.

Basic Information

Product Name	Lucanthone Hydrochloride
CAS No.	548-57-2
Molecular Formula	C₂₀H₂₄N₂OS•HCl
Molecular Weight	376.94 g/mol
Synonyms	Miracil D; Nilodin; 1-[(2-Diethylamino)ethylamino]-4-methylthioxanthen-9-one hydrochloride; NSC-14574; Lucanthone HCl; 1-[[2-(Diethylamino)ethyl]amino]-4-methyl-9H-thioxanthen-9-one hydrochloride; BW 57-323; RP 3359
EINECS	Contact for details

Quality Control

Our Lucanthone Hydrochloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and tests for residual solvents and heavy metals. A Certificate of Analysis (COA) detailing all specifications and results is provided to ensure traceability and compliance with your research or development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.