Description

7-Ethyl-3,7-Dihydro-6-Methyl-5-Phenylpyrrolo[3,4-E]-1,4-Diazepin-2(1H)-One is a high-purity, advanced pharmaceutical intermediate belonging to the diazepine class of heterocyclic compounds. This compound is valued for its complex molecular architecture, which serves as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and manufacturers in the pharmaceutical and life sciences sectors for the development of new therapeutic agents, particularly in central nervous system (CNS) and neurological research.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of proprietary drug candidates and novel chemical entities.
• Research & Development (R&D): Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a core scaffold for constructing complex molecules with potential pharmacological activity.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and developing new synthetic methodologies.
• Reference Standard: Sourced for analytical purposes as a high-purity standard for method development and quality control.

Basic Information

Product Name	7-Ethyl-3,7-Dihydro-6-Methyl-5-Phenylpyrrolo[3,4-E]-1,4-Diazepin-2(1H)-One
CAS No.	57435-92-4
Molecular Formula	C₁₇H₁₉N₃O
Molecular Weight	281.35 g/mol
Synonyms	5-Phenyl-7-ethyl-6-methyl-1,3,4,7-tetrahydropyrrolo[3,4-e][1,4]diazepin-2-one; 7-Ethyl-6-methyl-5-phenyl-1,3,4,7-tetrahydropyrrolo[3,4-e][1,4]diazepin-2(5H)-one; Pyrrolodiazepinone derivative; Diazepine intermediate; CAS 57435-92-4
EINECS	Contact for details

Quality Control

Our 7-Ethyl-3,7-Dihydro-6-Methyl-5-Phenylpyrrolo[3,4-E]-1,4-Diazepin-2(1H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D and manufacturing. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.