Description

L-2-Amino-3-(5-Hydroxyindolyl)Propionic Acid Ethyl Ester Hydrochloride is a specialized, high-purity chemical building block essential for advanced organic synthesis. This compound is a protected derivative of 5-hydroxytryptophan, offering a critical intermediate for researchers and manufacturers in the pharmaceutical and life sciences sectors. It is primarily utilized in the development of novel therapeutic agents, particularly those targeting neurological pathways and serotonin-related disorders.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those with indole-based structures for central nervous system (CNS) research.
• Biochemical Research: Used as a protected amino acid derivative in peptide synthesis and for studying neurotransmitter biosynthesis and metabolism.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Organic Synthesis Building Block: Employed in medicinal chemistry for the construction of more complex molecules due to its reactive amine and ester functional groups.
• Neuroscience Studies: Utilized in research models investigating serotonin synthesis, release, and reuptake mechanisms.

Basic Information

Product Name	L-2-Amino-3-(5-Hydroxyindolyl)Propionic Acid Ethyl Ester Hydrochloride
CAS No.	57432-62-9
Molecular Formula	C₁₄H₁₉ClN₂O₄
Molecular Weight	314.76 g/mol
Synonyms	5-Hydroxy-L-tryptophan ethyl ester hydrochloride; L-5-HTP-OEt HCl; Ethyl L-5-hydroxytryptophanate hydrochloride; (S)-2-Amino-3-(5-hydroxy-1H-indol-3-yl)propanoic acid ethyl ester hydrochloride; 5-Hydroxy-L-tryptophan ethyl ester HCl; 5-HTP ethyl ester hydrochloride; L-5-Hydroxytryptophan ethyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our L-2-Amino-3-(5-Hydroxyindolyl)Propionic Acid Ethyl Ester Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements for research and pharmaceutical development. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert conditions after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation	[α]²⁰D: Specific range available on COA
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.