Description

3-Amino-2-Methyl-Benzyl-D2 Bromide Hydrobromide is a high-purity, deuterated organic salt of significant value in advanced chemical synthesis and research. This compound is specifically designed for applications requiring isotopic labeling, offering enhanced stability and traceability in metabolic and pharmacokinetic studies. It is an essential building block for pharmaceutical researchers, analytical chemists, and manufacturers developing novel active pharmaceutical ingredients (APIs) and deuterated drug candidates.

Application

• Deuterated Pharmaceutical Intermediate: A critical precursor in the synthesis of deuterium-labeled drug molecules for improved metabolic stability and reduced toxicity profiles.
• Metabolic Pathway Tracer: Used in mass spectrometry and NMR-based studies to track and elucidate metabolic pathways and drug distribution in biological systems.
• Reference Standard: Serves as a high-purity analytical standard for method development and validation in quality control laboratories.
• Organic Synthesis Building Block: Utilized in the preparation of complex organic molecules, particularly those requiring a functionalized, deuterated benzylamine moiety.
• Isotope Effect Research: Enables fundamental research into kinetic isotope effects (KIE) in chemical and enzymatic reactions.
• Precursor for Radiolabeling: Acts as a starting material for the synthesis of tritium- or carbon-14-labeled compounds for advanced radiotracer studies.

Basic Information

Product Name	3-Amino-2-Methyl-Benzyl-D2 Bromide Hydrobromide
CAS No.	57414-77-4
Molecular Formula	C9H11D2Br2N
Molecular Weight	307.01 g/mol
Synonyms	2-Methyl-3-aminobenzyl-d2 Bromide Hydrobromide; 1-(Bromomethyl)-2-methyl-3-amino-d2-benzene Hydrobromide; 3-Amino-2-methylbenzyl-α,α-d2 Bromide Hydrobromide; (3-Amino-2-methylphenyl)methan-d2-yl Bromide Hydrobromide; Deuterated 3-Amino-2-methylbenzyl Bromide HBr Salt; 3-AMBB-d2 HBr; 57414-77-4
EINECS	Contact for details

Quality Control

Our 3-Amino-2-Methyl-Benzyl-D2 Bromide Hydrobromide is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including NMR, HPLC, and mass spectrometry, to confirm identity, chemical purity, and isotopic enrichment. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring full traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere or in a controlled, low-humidity environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.