Description

Trimethyl[[(1R)-5β-Methyl-2α-Isopropenylcyclohexyl]Oxy]Silane is a specialized organosilicon compound featuring a chiral, terpene-derived cyclohexyloxy moiety. This unique structure makes it a valuable intermediate and protecting group reagent in advanced organic synthesis, particularly for introducing silicon functionalities or masking hydroxyl groups under mild conditions. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors who require high-purity chiral building blocks for developing active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where specific stereochemistry is critical for bioactivity.
• Fine Chemical Production: Acts as a versatile building block for fragrances, flavors, and other specialty chemicals requiring the terpene structural motif.
• Silicon Chemistry Research: Employed in academic and industrial R&D for studying silylation reactions and developing new organosilicon compounds.
• Polymer Modification: Can be used to introduce functional silane groups into polymer chains, modifying surface properties or enabling cross-linking.
• Protecting Group in Multi-step Synthesis: The silyl ether group effectively protects alcohol functionalities during complex synthetic sequences.

Basic Information

Product Name	Trimethyl[[(1R)-5β-Methyl-2α-Isopropenylcyclohexyl]Oxy]Silane
CAS No.	57396-86-8
Molecular Formula	C13H26OSi
Molecular Weight	226.43 g/mol
Synonyms	(1R)-5β-Methyl-2α-isopropenylcyclohexyloxytrimethylsilane; Trimethyl[(1R,2S,5R)-5-Methyl-2-(1-methylethenyl)cyclohexyloxy]silane; (-)-Menth-1-en-8-yloxytrimethylsilane; (1R)-p-Menth-1-en-8-yloxytrimethylsilane; Terpene-derived silyl ether; Chiral cyclohexyloxy silane; TMS ether of terpene alcohol
EINECS	Contact for details

Quality Control

Our Trimethyl[[(1R)-5β-Methyl-2α-Isopropenylcyclohexyl]Oxy]Silane is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical and chiral purity, meeting the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Chiral Purity (Chiral GC/HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.