Description

p-(Trimethylsilyl)Phenylmethanethiol is a specialized organosilicon compound featuring a thiol functional group protected by a trimethylsilyl-substituted phenyl ring. This unique structure makes it a valuable building block and protecting group reagent in advanced organic synthesis, particularly for introducing sulfur-containing moieties with enhanced stability. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries who require high-purity intermediates for developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of novel drug candidates, especially those containing thioether or disulfide linkages.
• Ligand Precursor: Used in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Polymer Modification: Acts as a functional monomer or chain-transfer agent in the production of specialty silicones and sulfur-functionalized polymers.
• Surface Functionalization Agent: Employed to modify material surfaces (e.g., silica, gold nanoparticles) via thiol chemistry for sensor or coating applications.
• Protecting Group Chemistry: Utilized as a protecting group for thiols in multi-step synthetic sequences, offering selective deprotection.
• Agrochemical Synthesis: A building block for creating new active ingredients in crop protection agents.

Basic Information

Product Name	p-(Trimethylsilyl)Phenylmethanethiol
CAS No.	57337-85-6
Molecular Formula	C10H16SSi
Molecular Weight	196.39 g/mol
Synonyms	(4-(Trimethylsilyl)phenyl)methanethiol; (p-Trimethylsilylbenzyl)mercaptan; 4-(Trimethylsilyl)benzyl Mercaptan; α-Mercapto-p-trimethylsilyltoluene; p-(Trimethylsilyl)benzylthiol; 57337-85-6; (4-Trimethylsilylphenyl)methanethiol
EINECS	Contact for details

Quality Control

Our p-(Trimethylsilyl)Phenylmethanethiol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to support your R&D and production quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C to minimize oxidation and degradation. Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.