Description

2-Methyl-6-Trifluoromethyl-1H-Indole CAS NO 57330-48-0 is a high-value, multi-functional indole derivative characterized by its trifluoromethyl and methyl substituents. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in modern synthetic chemistry. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in areas like kinase inhibitors and central nervous system (CNS) agents.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging the biological activity of the indole scaffold.
• Material Science Research: Acts as a precursor for functionalized organic molecules used in organic light-emitting diodes (OLEDs) and other electronic materials.
• Chemical Research & Development: Serves as a versatile building block for medicinal chemistry, enabling structure-activity relationship (SAR) studies and library synthesis.
• Fluorinated Compound Production: The trifluoromethyl group makes it a valuable starting material for introducing fluorine into target molecules to enhance metabolic stability and lipophilicity.

Basic Information

Product Name	2-Methyl-6-Trifluoromethyl-1H-Indole
CAS No.	57330-48-0
Molecular Formula	C10H8F3N
Molecular Weight	199.17 g/mol
Synonyms	6-(Trifluoromethyl)-2-methyl-1H-indole; 2-Methyl-6-(trifluoromethyl)indole; 1H-Indole, 2-methyl-6-(trifluoromethyl)-; 2-Methyl-6-trifluoromethylindole; 6-Trifluoromethyl-2-methylindole; 2-Methyl-6-trifluoromethyl-1H-indole; 57330-48-0; MFCD11871103
EINECS	Contact for details

Quality Control

Our 2-Methyl-6-Trifluoromethyl-1H-Indole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistent quality suitable for research and commercial synthesis. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specification parameters. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.