Description

[[(20R)-5α-Pregnane-3β,17,20,21-Tetryl]Tetrakis(Oxy)]Tetrakis(Trimethylsilane) is a high-purity, fully protected steroid derivative, specifically designed as a critical synthetic intermediate. This compound matters for enabling complex organic synthesis with high selectivity and yield, particularly in the construction of steroidal frameworks. It is primarily needed by pharmaceutical R&D teams, advanced organic chemists, and fine chemical manufacturers working on novel drug candidates, hormone analogs, and sophisticated chemical probes.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex steroid-based active pharmaceutical ingredients (APIs).
• Research Chemical: Used in academic and industrial laboratories for the study of steroid metabolism, receptor binding, and structure-activity relationships (SAR).
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in steroid analysis.
• Advanced Organic Synthesis: Employed in protecting group strategies for the selective functionalization of polyhydroxylated steroid molecules.
• Biochemical Probe Development: Utilized in creating labeled or modified steroid compounds for biological and diagnostic research.

Basic Information

Product Name	[(20R)-5α-Pregnane-3β,17,20,21-Tetryl]Tetrakis(Oxy)]Tetrakis(Trimethylsilane)
CAS No.	57325-84-5
Molecular Formula	C33H72O4Si4
Molecular Weight	629.31 g/mol
Synonyms	5α-Pregnane-3β,17,20,21-tetrol, 3,17,20,21-tetrakis(trimethylsilyl) ether, (20R)-; 3β,17,20,21-Tetrakis(trimethylsiloxy)-5α-pregnane; Pregnane-3β,17,20,21-tetrol, tetra-TMS derivative; 5α-Pregnane-3β,17β,20R,21-tetrol, tetra(trimethylsilyl) ether; TMS-protected 5α-pregnane-3β,17,20,21-tetrol; Steroid TMS ether intermediate; Tetrakis-O-trimethylsilyl-5α-pregnane-3β,17,20,21-tetrol
EINECS	Contact for details

Quality Control

Our [[(20R)-5α-Pregnane-3β,17,20,21-Tetryl]Tetrakis(Oxy)]Tetrakis(Trimethylsilane) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.