Description

4,8-Isoquinolinediol, 1,2,3,4-Tetrahydro-2-Methyl-, (4R)- is a chiral, tetrahydroisoquinoline derivative of significant interest in advanced organic synthesis. This compound serves as a critical chiral building block and synthetic intermediate for the development of complex molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), fine chemicals, and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of potential therapeutic agents and active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Utilized as a chiral auxiliary or precursor in stereoselective reactions to construct complex molecular architectures.
• Medicinal Chemistry Research: Serves as a core scaffold in drug discovery programs for designing and optimizing new chemical entities.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, agrochemicals, and other high-value compounds.
• Academic & Industrial R&D: Used in research laboratories for methodological development and exploring new reaction pathways.

Basic Information

Product Name	4,8-Isoquinolinediol, 1,2,3,4-Tetrahydro-2-Methyl-, (4R)-
CAS No.	57236-57-4
Molecular Formula	C10H13NO2
Molecular Weight	179.22 g/mol
Synonyms	(4R)-1,2,3,4-Tetrahydro-2-methyl-4,8-isoquinolinediol; (R)-1,2,3,4-Tetrahydro-2-methyl-4,8-isoquinolinediol; (4R)-2-Methyl-1,2,3,4-tetrahydro-4,8-isoquinolinediol; 4,8-Isoquinolinediol, 1,2,3,4-tetrahydro-2-methyl-, (4R)-; Tetrahydro-2-methyl-4,8-isoquinolinediol (4R-isomer); Chiral Tetrahydroisoquinoline Diol
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide material with a focus on high chiral purity and chemical identity, supported by advanced analytical techniques. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and other critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0% ee
Loss on Drying	≤ 1.0 %
Residue on Ignition	≤ 0.1 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.