Description

(S)-1-[(3,4-Dihydroxyphenyl)Methyl]-1,2,3,4-Tetrahydro-2-Methylisoquinoline-6,7-Diol is a high-purity chiral isoquinoline alkaloid derivative of significant interest in advanced pharmaceutical research and development. This compound matters as a sophisticated synthetic intermediate or reference standard for the creation of novel bioactive molecules targeting neurological and cardiovascular pathways. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical sectors working on innovative drug candidates.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of potential therapeutic agents.
• Biochemical Research: Used as a reference standard or probe in studies of enzyme inhibition and receptor binding assays.
• Neurological Research: Investigated for its potential role as a precursor to compounds affecting dopaminergic or adrenergic systems.
• Asymmetric Synthesis: Utilized in the development of chiral catalysts or ligands due to its defined stereochemistry.
• Reference Material: Employed in analytical laboratories for method development and quality control of related substances.
• Academic Research: Used in university and institutional labs for fundamental studies in medicinal chemistry and organic synthesis.

Basic Information

Product Name	(S)-1-[(3,4-Dihydroxyphenyl)Methyl]-1,2,3,4-Tetrahydro-2-Methylisoquinoline-6,7-Diol
CAS No.	57231-31-9
Molecular Formula	C₁₇H₁₉NO₄
Molecular Weight	301.34 g/mol
Synonyms	(S)-Norcoclaurine; (S)-1-[(3,4-Dihydroxyphenyl)methyl]-1,2,3,4-tetrahydro-2-methyl-6,7-isoquinolinediol; (S)-6,7-Dihydroxy-1-(3,4-dihydroxybenzyl)-2-methyl-1,2,3,4-tetrahydroisoquinoline; (S)-2-Methylnorcoclaurine; (S)-4-[(1S)-1,2,3,4-Tetrahydro-6,7-dihydroxy-2-methyl-1-isoquinolyl]methyl]-1,2-benzenediol; (S)-1-(3,4-Dihydroxybenzyl)-2-methyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline
EINECS	Contact for details

Quality Control

Our (S)-1-[(3,4-Dihydroxyphenyl)Methyl]-1,2,3,4-Tetrahydro-2-Methylisoquinoline-6,7-Diol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to minimize oxidation and degradation. The container should be kept in a cool, dry, and well-ventilated area, separate from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.