Description

2,5-Dichlorothiophene-3-Sulfonyl Chloride is a high-value, multi-functional chemical intermediate characterized by its reactive sulfonyl chloride group and halogenated thiophene backbone. This compound matters for its critical role as a versatile building block in the synthesis of complex molecules, enabling the introduction of the sulfonamide moiety. It is primarily needed by research and development teams and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries for creating new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of sulfonamide-based drug candidates, including potential enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the thiophene-sulfonamide structure confers specific biological activity.
• Material Science Precursor: Serves as a monomer or functionalization agent in the production of advanced polymers, dyes, and electronic materials.
• Chemical Research (R&D): Essential reagent in medicinal and organic chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Ligand and Catalyst Development: Utilized to create specialized ligands for metal catalysis or functionalized surfaces.

Basic Information

Product Name	2,5-Dichlorothiophene-3-Sulfonyl Chloride
CAS No.	56946-83-9
Molecular Formula	C4HCl3O2S2
Molecular Weight	255.53 g/mol
Synonyms	3-Chlorosulfonyl-2,5-dichlorothiophene; 2,5-Dichloro-3-thiophenesulfonyl chloride; 2,5-Dichlorothiophene-3-sulfonic acid chloride; 2,5-Dichloro-3-thienylsulfonyl chloride; 2,5-Dichloro-thiophene-3-sulfonyl chloride; 2,5-Dichloro-3-sulfothiophene chloride
EINECS	Contact for details

Quality Control

Our 2,5-Dichlorothiophene-3-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases, amines, alcohols, and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.