Description

Chloromethyl Thiophene (CAS NO 56909-07-0) is a versatile and reactive heterocyclic building block essential for advanced organic synthesis. Its core value lies in the chloromethyl group, which serves as a key electrophilic site for constructing more complex molecular architectures through nucleophilic substitution and cross-coupling reactions. This intermediate is particularly critical for researchers and manufacturers in the pharmaceutical and agrochemical sectors developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those containing thiophene-based heterocycles for therapeutic applications.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides, where the thiophene moiety contributes to biological activity.
• Material Science & Functional Polymers: Serves as a monomer or functionalization agent for creating conductive polymers, organic semiconductors, and specialty polymers with tailored electronic properties.
• Ligand & Catalyst Development: Employed in the preparation of novel ligands for metal catalysis and organocatalysts used in asymmetric synthesis.
• Dye & Pigment Manufacturing: Acts as an intermediate in the synthesis of complex organic dyes and pigments, especially those requiring specific light-absorption characteristics.
• Research & Development: A fundamental reagent in academic and industrial R&D labs for exploring new chemical entities and reaction pathways in medicinal and synthetic chemistry.

Basic Information

Product Name	Chloromethyl Thiophene
CAS No.	56909-07-0
Molecular Formula	C5H5ClS
Molecular Weight	132.61 g/mol
Synonyms	2-(Chloromethyl)thiophene; Thiophene-2-ylmethyl chloride; 2-Thienylmethyl chloride; (2-Thienyl)methyl chloride; 2-Chloromethylthiophene; α-Chloro-2-thiophenemethane; 2-Thiophenemethyl chloride
EINECS	Contact for details

Quality Control

Our Chloromethyl Thiophene is produced under stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets the high standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing specific results for purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.