Description

4-(Methoxymethylphosphinyl)-n-(Trifluoroacetyl)-L-Abu-L-Ala-L-Ala-Ome is a specialized synthetic peptide derivative containing a phosphinyl group and a trifluoroacetyl protecting group. This compound is of significant value in advanced pharmaceutical research and development, particularly in the synthesis of complex peptide-based molecules and protease inhibitors. It is primarily needed by R&D laboratories and production facilities in the pharmaceutical and biotechnology sectors for developing novel therapeutic agents and conducting structure-activity relationship (SAR) studies.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex peptide drugs and active pharmaceutical ingredients (APIs).
• Protease Inhibitor Research: Used in the development and study of enzyme inhibitors targeting specific proteolytic pathways.
• Chemical Biology: Serves as a tool compound for studying protein-protein interactions and enzyme mechanisms.
• Peptide Mimetic Synthesis: Employed in creating peptidomimetics with enhanced stability and bioavailability.
• Medicinal Chemistry: Utilized in lead optimization and the discovery of new therapeutic candidates.
• Bioconjugation: Acts as a specialized reagent for introducing phosphinyl motifs into biomolecules.

Basic Information

Product Name	4-(Methoxymethylphosphinyl)-n-(Trifluoroacetyl)-L-Abu-L-Ala-L-Ala-Ome
CAS No.	56890-06-3
Molecular Formula	C18H29F3N4O8P
Molecular Weight	517.42 g/mol
Synonyms	N-[(2S)-1-[[(2S)-1-[[(2S)-4-(Methoxymethylphosphinyl)-2-[[2,2,2-trifluoroacetyl]amino]butanoyl]amino]propanoyl]amino]propan-2-yl] 2,2,2-trifluoroacetate; L-Abu(POM)-L-Ala-L-Ala-OMe TFA; 4-(Methoxymethylphosphinyl)-N-(trifluoroacetyl)-L-2-aminobutyryl-L-alanyl-L-alanine methyl ester; Abu(POM)-Ala-Ala-OMe; Peptide derivative 56890-06-3; Phosphinyl peptide trifluoroacetate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide material with a typical purity of ≥95% (by HPLC), suitable for research and development applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request. Our quality management system supports the needs of customers operating under cGMP and ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). For long-term storage, consider storing under an inert atmosphere. Allow the container to reach room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.