Description

(S)-1,2,3,4-Tetrahydro-4-(4-Hydroxyphenyl)-6-Methoxy-7-Isoquinolinol is a high-purity chiral isoquinoline derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical synthetic intermediate and a key scaffold for designing novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of central nervous system (CNS) drugs, enzyme inhibitors, and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of potential drug candidates targeting neurological and psychiatric disorders.
• Biochemical Research: Used as a reference standard or probe in enzymatic and receptor binding studies due to its specific stereochemistry and functional groups.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity of new chemical entities.
• Asymmetric Synthesis: Employed in the development of chiral catalysts or as a starting material for synthesizing complex, enantiomerically pure molecules.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic chemistry and pharmacology.

Basic Information

Product Name	(S)-1,2,3,4-Tetrahydro-4-(4-Hydroxyphenyl)-6-Methoxy-7-Isoquinolinol
CAS No.	56847-08-6
Molecular Formula	C16H17NO3
Molecular Weight	271.31 g/mol
Synonyms	(S)-4-(4-Hydroxyphenyl)-6-methoxy-1,2,3,4-tetrahydro-7-isoquinolinol; (S)-THIQ derivative; (S)-6-Methoxy-7-hydroxy-4-(4-hydroxyphenyl)-1,2,3,4-tetrahydroisoquinoline; (S)-4-(p-Hydroxyphenyl)-6-methoxy-7-hydroxy-1,2,3,4-tetrahydroisoquinoline; (S)-7-Isoquinolinol, 1,2,3,4-tetrahydro-4-(4-hydroxyphenyl)-6-methoxy-; (S)-enantiomer of a tetrahydroisoquinoline alkaloid precursor
EINECS	Contact for details

Quality Control

Our (S)-1,2,3,4-Tetrahydro-4-(4-Hydroxyphenyl)-6-Methoxy-7-Isoquinolinol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure high chemical and enantiomeric purity suitable for research applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to ensure full traceability and compliance with your research protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.