Description

Octahydro-2,7-Bis[(Trimethylsilyl)Oxy]-5H,10H-Dipyrrolo[1,2-A:1',2'-D]Pyrazine-5,10-Dione is a specialized organosilicon-protected derivative of a diketopiperazine core structure. This compound serves as a critical synthetic intermediate and protecting group reagent in advanced organic synthesis, enabling precise chemical transformations. It is primarily required by pharmaceutical R&D and fine chemical synthesis teams for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates, particularly those containing modified peptide or diketopiperazine scaffolds.
• Peptidomimetic Research: Used to create and protect diketopiperazine (DKP) units, which are important structural motifs in medicinal chemistry for modulating biological activity.
• Organosilicon Chemistry: Serves as a reagent featuring trimethylsilyl (TMS) protecting groups for sensitive hydroxyl functions during multi-step synthetic sequences.
• Asymmetric Synthesis: Potential chiral template or auxiliary in the preparation of enantiomerically pure compounds for agrochemical and pharmaceutical applications.
• Chemical Biology Probes: Useful in the development of molecular probes to study enzyme mechanisms or protein-protein interactions involving cyclic dipeptide structures.
• Material Science Precursor: Can be utilized in the development of novel organic-silicon hybrid materials with specific functional properties.

Basic Information

Product Name	Octahydro-2,7-Bis[(Trimethylsilyl)Oxy]-5H,10H-Dipyrrolo[1,2-A:1',2'-D]Pyrazine-5,10-Dione
CAS No.	56817-96-0
Molecular Formula	C16H30N2O4Si2
Molecular Weight	370.60 g/mol
Synonyms	2,7-Bis(trimethylsiloxy)-octahydro-dipyrrolo[1,2-a:1',2'-d]pyrazine-5,10-dione; 5,10-Dioxo-octahydro-2,7-bis(trimethylsiloxy)dipyrrolo[1,2-a:1',2'-d]pyrazine; TMS-protected Diketopiperazine Diol; 1,4-Diaza-2,7-disilabicyclo[4.3.0]nonane-3,8-dione derivative; Bis-O-TMS Diketopiperazine; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our Octahydro-2,7-Bis[(Trimethylsilyl)Oxy]-5H,10H-Dipyrrolo[1,2-A:1',2'-D]Pyrazine-5,10-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening to prevent degradation from ambient moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.