Description

6-o-[6-Deoxy-2-O,3-O,4-o-Tris(Trimethylsilyl)-α-L-Mannopyranosyl]-2-O,3-O,4-O,5-o-Tetrakis(Trimethylsilyl)-D-Glucose is a highly functionalized, fully protected disaccharide derivative, serving as a critical advanced intermediate in complex organic synthesis. Its value lies in providing a pre-assembled, selectively silylated carbohydrate core, which significantly streamlines the synthesis of complex glycoconjugates and natural products. This compound is essential for researchers and manufacturers in pharmaceutical development, particularly for creating novel glycosylated drug candidates, and in advanced carbohydrate chemistry for probing biological recognition events.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex glycosylated active pharmaceutical ingredients (APIs) and prodrugs.
• Glycoconjugate Synthesis: Used in the preparation of glycopeptides, glycolipids, and other biologically relevant conjugates for drug discovery and biological studies.
• Carbohydrate Chemistry Research: Serves as a versatile precursor for studying glycosylation reactions, protecting group strategies, and enzyme-substrate interactions.
• Oligosaccharide Assembly: An advanced intermediate in the modular, stepwise construction of defined oligosaccharide chains.
• Chemical Biology Probes: Utilized to develop labeled or modified carbohydrate probes for investigating cellular recognition and signaling pathways.
• Standards and Reference Materials: Acts as a high-purity analytical standard for method development and quality control in carbohydrate analysis.

Basic Information

Product Name	6-o-[6-Deoxy-2-O,3-O,4-o-Tris(Trimethylsilyl)-α-L-Mannopyranosyl]-2-O,3-O,4-O,5-o-Tetrakis(Trimethylsilyl)-D-Glucose
CAS No.	56784-10-2
Molecular Formula	C39H86O11Si7
Molecular Weight	915.71 g/mol
Synonyms	1,2,3,4,5-Penta-O-trimethylsilyl-6-O-[2,3,4-tri-O-trimethylsilyl-6-deoxy-α-L-mannopyranosyl]-D-glucopyranose; D-Glucose, 6-O-[6-deoxy-2,3,4-tri-O-(trimethylsilyl)-α-L-mannopyranosyl]-2,3,4,5-tetra-O-(trimethylsilyl)-; Fully Silylated 6-O-(α-L-Rhamnopyranosyl)-D-Glucose Derivative; Per-TMS Protected Glc-α-(1→6)-Man Disaccharide; Heptakis(trimethylsilyl) Glc(α1-6)Man Derivative
EINECS	Contact for details

Quality Control

Our production of this advanced synthetic intermediate adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for your research and development. Each lot is characterized using advanced analytical techniques including NMR (¹H, ¹³C), HPLC, and mass spectrometry to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid or viscous oil
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.