Description

(4S)-1,2,3,4-Tetrahydro-4-(4-Hydroxyphenyl)-6-Methoxy-2-(Trifluoroacetyl)-7-Isoquinolinol is a high-purity chiral isoquinoline derivative, a critical synthetic intermediate in advanced pharmaceutical research and development. Its value lies in its complex molecular architecture, which serves as a key building block for creating novel, biologically active compounds. This product is essential for R&D chemists and process development scientists in the pharmaceutical and fine chemical industries, particularly those focused on central nervous system (CNS) agents and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of potential drug candidates, particularly for neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel therapeutic targets.
• Process Chemistry Development: Serves as a critical starting material for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Asymmetric Synthesis: Utilized as a chiral scaffold or reagent in the synthesis of enantiomerically pure compounds.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Academic & Institutional Research: Employed in universities and research institutes for exploring new chemical entities and reaction methodologies.

Basic Information

Product Name	(4S)-1,2,3,4-Tetrahydro-4-(4-Hydroxyphenyl)-6-Methoxy-2-(Trifluoroacetyl)-7-Isoquinolinol
CAS No.	56771-97-2
Molecular Formula	C19H16F3NO4
Molecular Weight	379.33 g/mol
Synonyms	7-Isoquinolinol, 1,2,3,4-tetrahydro-4-(4-hydroxyphenyl)-6-methoxy-2-(trifluoroacetyl)-, (4S)-; (4S)-4-(4-Hydroxyphenyl)-6-methoxy-2-(trifluoroacetyl)-1,2,3,4-tetrahydro-7-isoquinolinol; (S)-4-(4-Hydroxyphenyl)-6-methoxy-2-(trifluoroacetyl)-1,2,3,4-tetrahydroisoquinolin-7-ol; Trifluoroacetyl Tetrahydroisoquinolinol Derivative; Chiral Tetrahydroisoquinoline Intermediate
EINECS	Contact for details

Quality Control

Our (4S)-1,2,3,4-Tetrahydro-4-(4-Hydroxyphenyl)-6-Methoxy-2-(Trifluoroacetyl)-7-Isoquinolinol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to meet the exacting standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) with full chromatographic data is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.