Description

(R)-2-Chloro-1-Phenylethanol is a chiral chlorohydrin building block of significant importance in asymmetric synthesis. Its enantiopure form is highly valued for the preparation of optically active pharmaceuticals and fine chemicals. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity chiral intermediates.

Application

• Chiral Pharmaceutical Intermediate: A key precursor in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), particularly for β-adrenergic blockers and other chiral drugs.
• Asymmetric Synthesis Building Block: Used in stereoselective reactions, including nucleophilic substitutions and ring-opening reactions, to introduce the (R)-configured phenylethanol moiety.
• Agrochemical Synthesis: Serves as an intermediate in the production of certain chiral herbicides and pesticides where specific stereochemistry is required for biological activity.
• Ligand and Catalyst Preparation: Utilized in the development of chiral ligands for asymmetric catalysis and organocatalysts.
• Fine Chemical and Flavor/Fragrance Intermediate: Employed in the synthesis of complex, high-value specialty chemicals and aroma compounds.
• Academic and R&D Laboratories: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	(R)-2-Chloro-1-Phenylethanol
CAS No.	56751-12-3
Molecular Formula	C8H9ClO
Molecular Weight	156.61 g/mol
Synonyms	(R)-2-Chloro-1-phenylethanol; (R)-2-Chloro-1-phenylethan-1-ol; (R)-α-(Chloromethyl)benzyl alcohol; (R)-1-Phenyl-2-chloroethanol; (R)-Styrene chlorohydrin; (R)-Phenylethylene chlorohydrin; (R)-2-Chloro-2-phenylethanol; (R)-β-Chloro-α-phenylethanol
EINECS	Contact for details

Quality Control

Our (R)-2-Chloro-1-Phenylethanol is produced under strict quality management systems. Each batch is subjected to rigorous analytical testing, including chiral purity analysis (HPLC/GC), to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Specific Rotation [α]	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.