Description

3-Bromo-6-Mercaptopyridine is a versatile heterocyclic building block featuring both bromine and thiol functional groups, enabling selective cross-coupling and substitution reactions. This compound is critical for the efficient synthesis of complex molecules in pharmaceutical and agrochemical research. It is primarily utilized by R&D chemists and process development scientists in the life sciences sector for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides due to its reactive halogen and sulfur sites.
• Ligand Precursor: Serves as a precursor for metal-chelating ligands in catalysis and material science applications.
• Functional Material Research: Employed in the creation of organic electronic materials, conductive polymers, and self-assembled monolayers (SAMs).
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions.
• Bioconjugation Chemistry: The thiol group allows for site-specific modification of proteins, peptides, and other biomolecules.

Basic Information

Product Name	3-Bromo-6-Mercaptopyridine
CAS No.	56673-34-8
Molecular Formula	C5H4BrNS
Molecular Weight	190.06 g/mol
Synonyms	6-Mercapto-3-bromopyridine; 3-Bromo-6-pyridinethiol; 3-Bromo-6-thiopyridinol; 3-Bromopyridine-6-thiol; 3-Bromo-6-mercapto-pyridine; 6-Bromo-3-mercaptopyridine (incorrect but common misnomer); Pyridine, 3-bromo-6-mercapto-
EINECS	Contact for details

Quality Control

Our 3-Bromo-6-Mercaptopyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and degradation. Keep the container in a cool, dry, and well-ventilated place away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.