Description

3-Acetylamino-5-Methyl-1H-Indole-2-Carboxylic Acid is a high-purity, synthetically derived indole derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its functionalized indole core, which is essential for constructing complex molecular architectures with targeted biological activity. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemical intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides due to its bioactive indole scaffold.
• Biochemical Research: Serves as a standard or reference compound in metabolic and enzymatic studies.
• Material Science: Investigated as a monomer or functional additive for specialty polymers and organic electronic materials.
• Academic & Contract Research: Employed in university and CRO laboratories for method development and exploratory synthetic chemistry.

Basic Information

Product Name	3-Acetylamino-5-Methyl-1H-Indole-2-Carboxylic Acid
CAS No.	56545-54-1
Molecular Formula	C₁₃H₁₄N₂O₃
Molecular Weight	246.26 g/mol
Synonyms	3-Acetamido-5-methyl-1H-indole-2-carboxylic acid; 5-Methyl-3-acetylaminoindole-2-carboxylic acid; 2-Carboxy-5-methyl-3-acetamidoindole; N-[2-(Carboxy)-5-methyl-1H-indol-3-yl]acetamide; 3-(Acetylamino)-5-methyl-1H-indole-2-carboxylic acid; 56545-54-1; 3-Acetylamino-5-methylindole-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 3-Acetylamino-5-Methyl-1H-Indole-2-Carboxylic Acid adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support compliance with cGMP and ISO 9001 standards for research and commercial-scale supply.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.