Description

n-(p-Toluenesulfonyloxy)Phthalimide is a specialized organic chemical intermediate, primarily recognized for its role as a versatile tosylating and phthalimido-transfer reagent. Its value lies in enabling efficient synthetic pathways for the construction of complex molecules, particularly in the development of pharmaceuticals and advanced materials. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce protected amine functionalities or specific sulfonate groups with high selectivity.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds requiring phthalimide or tosylate protection.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators that incorporate sulfonamide or imide structures.
• Polymer Chemistry: Serves as a monomer or cross-linking agent in the development of specialty polymers with specific thermal or chemical resistance properties.
• Organic Synthesis Reagent: Employed as a tosylating agent to convert alcohols into tosylates or to introduce the phthalimido group as a protected amine equivalent in multi-step syntheses.
• Dye and Pigment Manufacturing: Intermediate in the synthesis of complex organic colorants and photostable pigments.
• Research & Development: A valuable tool in academic and industrial R&D labs for methodological studies and the discovery of new chemical entities.

Basic Information

Product Name	n-(p-Toluenesulfonyloxy)Phthalimide
CAS No.	56530-39-3
Molecular Formula	C15H11NO5S
Molecular Weight	317.32 g/mol
Synonyms	N-(4-Methylbenzenesulfonyloxy)phthalimide; N-(p-Tolylsulfonyloxy)phthalimide; Phthalimide, N-[(4-methylphenyl)sulfonyl]oxy]-; Tosyloxyphthalimide; N-Tosyloxyphthalimide; N-(Tosyloxy)phthalimide; N-OTs Phthalimide; 4-Methyl-N-(phthalimidooxy)benzenesulfonamide
EINECS	Contact for details

Quality Control

Our n-(p-Toluenesulfonyloxy)Phthalimide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay, impurity profile, and physical characteristics are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	142 - 147 °C
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.