Description

1-(2-Fluoro-1,1'-Biphenyl-4-Yl)Ethanol is a high-value fluorinated biphenyl derivative, serving as a critical chiral intermediate in advanced organic synthesis. Its molecular structure, featuring both a biphenyl core and a fluorine substituent, makes it essential for constructing complex molecules with specific steric and electronic properties. This compound is primarily sought by pharmaceutical R&D and fine chemical manufacturers for the development of active pharmaceutical ingredients (APIs) and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Liquid Crystal Material Precursor: Used in the research and production of fluorinated liquid crystals for advanced display technologies.
• Agrochemical Synthesis: Serves as an intermediate in creating new-generation fluorinated pesticides and herbicides with enhanced efficacy.
• Organic Light-Emitting Diode (OLED) Materials: Employed in the development of electron-transport or host materials for OLED devices.
• Asymmetric Catalysis Research: Utilized as a substrate or ligand precursor in the development of new chiral catalysts.
• Advanced Polymer Modifier: Incorporated to introduce fluorinated biphenyl units into high-performance polymers, improving their thermal and chemical stability.

Basic Information

Product Name	1-(2-Fluoro-1,1'-Biphenyl-4-Yl)Ethanol
CAS No.	56430-67-2
Molecular Formula	C14H13FO
Molecular Weight	216.25 g/mol
Synonyms	2-Fluoro-4-(1-hydroxyethyl)biphenyl; 1-(2-Fluorobiphenyl-4-yl)ethanol; 4-(1-Hydroxyethyl)-2-fluorobiphenyl; α-Methyl-2-fluoro[1,1'-biphenyl]-4-ethanol; (RS)-1-(2-Fluorobiphenyl-4-yl)ethanol; 2-Fluoro-4-(α-hydroxyethyl)biphenyl; Biphenyl-4-ethanol, 2-fluoro-α-methyl-; 1-(4-Biphenylyl)-2-fluoroethanol (ambiguous, verify structure)
EINECS	Contact for details

Quality Control

Our production of 1-(2-Fluoro-1,1'-Biphenyl-4-Yl)Ethanol adheres to strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity analysis, to ensure it meets the exacting standards required for pharmaceutical and advanced material applications. A Certificate of Analysis (COA) detailing purity, enantiomeric excess (if applicable), and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e. (or as specified)
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.