Description

7-Trifluoromethyloxindole is a high-value, fluorinated heterocyclic compound that serves as a critical synthetic intermediate. Its unique structure, featuring the oxindole core and a trifluoromethyl group, makes it indispensable for constructing complex molecules with enhanced biological activity and physicochemical properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of drug candidates targeting central nervous system (CNS) disorders, oncology, and inflammatory diseases.
• Agrochemical Research: Used in developing advanced herbicides, fungicides, and insecticides where the trifluoromethyl group improves metabolic stability and lipophilicity.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the creation of specialty polymers and advanced organic electronic materials.
• Chemical Biology Probe: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and as a scaffold for fragment-based drug discovery.
• Organic Synthesis Reagent: Employed in palladium-catalyzed cross-coupling reactions and other transformations to introduce the oxindole motif into complex molecules.

Basic Information

Product Name	7-Trifluoromethyloxindole
CAS No.	56341-40-3
Molecular Formula	C9H6F3NO
Molecular Weight	201.15 g/mol
Synonyms	1H-Indol-2-one, 7-(trifluoromethyl)-; 7-(Trifluoromethyl)-1H-indole-2,3-dione, 3-hydroxy derivative; 7-(Trifluoromethyl)oxindole; 7-Trifluoromethyl-2-indolinone; 2-Oxo-7-(trifluoromethyl)indoline; 7-Trifluoromethyl-1,3-dihydro-2H-indol-2-one
EINECS	Contact for details

Quality Control

Our 7-Trifluoromethyloxindole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.