Description

2,5-Ethano-2H-Azocino[4,3-B]Indole-6-Carboxylic Acid, 6-[(Acetyloxy)Me Thyl]-4-Ethylidene-1,3,4,5,6,7-Hexahydro-, Methyl Ester, [5S-[4E,5Alph A,6Beta]]- is a complex, stereochemically defined indole alkaloid derivative that serves as a critical advanced intermediate in modern organic synthesis. This compound matters for its role as a sophisticated building block in the development of novel pharmaceuticals and bioactive molecules, particularly those targeting neurological and oncological pathways. It is essential for research chemists and process development teams in the pharmaceutical, agrochemical, and fine chemical industries who require high-purity, structurally complex intermediates for their synthetic programs.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel indole-based drug candidates, particularly in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Process Chemistry Development: Serves as a critical intermediate in scaling up synthetic routes for active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Utilized in chiral pool synthesis due to its defined stereochemistry at multiple centers.
• Agrochemical Research: Potential intermediate for developing new crop protection agents with novel modes of action.
• Academic & Institutional Research: Used in universities and research institutes for exploring new chemical transformations and natural product synthesis.

Basic Information

Product Name	2,5-Ethano-2H-Azocino[4,3-B]Indole-6-Carboxylic Acid, 6-[(Acetyloxy)Me Thyl]-4-Ethylidene-1,3,4,5,6,7-Hexahydro-, Methyl Ester, [5S-[4E,5Alph A,6Beta]]-
CAS No.	56293-11-9
Molecular Formula	C20H23NO5
Molecular Weight	357.40 g/mol
Synonyms	Methyl (5S,6R)-6-(acetoxymethyl)-4-ethylidene-1,3,4,5,6,7-hexahydro-2,5-ethano-2H-azocino[4,3-b]indole-6-carboxylate; (5S,6R)-6-(Acetoxymethyl)-4-ethylidene-1,3,4,5,6,7-hexahydro-2,5-ethano-2H-azocino[4,3-b]indole-6-carboxylic acid methyl ester; 6-(Acetoxymethyl)-4-ethylidene-1,3,4,5,6,7-hexahydro-2,5-ethano-2H-azocino[4,3-b]indole-6-carboxylic acid methyl ester; [5S-(4E,5α,6β)]-6-[(Acetyloxy)methyl]-4-ethylidene-1,3,4,5,6,7-hexahydro-2,5-ethano-2H-azocino[4,3-b]indole-6-carboxylic acid methyl ester; Azocinoindole derivative 56293-11-9; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 2,5-Ethano-2H-Azocino[4,3-B]Indole-6-Carboxylic Acid, 6-[(Acetyloxy)Me Thyl]-4-Ethylidene-1,3,4,5,6,7-Hexahydro-, Methyl Ester, [5S-[4E,5Alph A,6Beta]]- is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support compliance with ICH guidelines for stability and impurity characterization. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Purity (HPLC, Area %)	≥ 97.0%
Single Maximum Impurity	≤ 1.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.